Dr Dimitrios Mavrelos

Consultant in Obstetrics, Gynaecology and Reproductive Medicine

University College London Hospital

Frozen–thawed embryo transfer (FET) calculator

Generates an approximate schedule for a frozen embryo transfer of a Day-5 blastocyst. The medicated pathway can start either from the downregulation cycle (Norethisterone-programmed, as in the stimulation cycle dates calculator) or directly from the treatment-cycle first day of bleed. The modified-natural pathway works from the first day of the period in the treatment cycle. Exact dates follow your clinic’s protocol.

Inputs

Day 1 of the cycle before treatment.
Leave blank to estimate it (~3 days after stopping Norethisterone). Enter your actual bleed date when known to refine the schedule.
10 d
Days from transfer to the beta-hCG blood test (clinic-dependent).

Schedule

Embryo transfer date
Pregnancy test date
Pregnancy scan (6w3d)
Estimated due date
StepDateNotes

Methods

In the medicated pathway, Norethisterone is taken from day 14 to day 25 of the downregulation cycle (as in the stimulation cycle dates calculator). A few days after stopping it, a withdrawal bleed marks day 1 of the treatment cycle. Oestradiol is started on day 3 of the bleed to build the lining, which is scanned at about cycle day 10 (~7 days of oestrogen); progesterone begins on cycle day 14, and a Day-5 blastocyst is transferred on the 6th day of progesterone (progesterone start + 5 days). A viability scan is booked at 6 weeks 3 days of gestation. In the modified-natural pathway the cycle is tracked from the first day of the period; an hCG trigger is given (estimated from cycle length, or entered), the day after the trigger is day 0 and progesterone is started, and a Day-5 blastocyst is transferred 5 days later (day 0 + 5). The estimated due date is the transfer date + (266 − embryo day) days. Intervals are idealised and vary between clinics and patients.

Disclaimer

This schedule is based on an idealised cycle and should only be used as a guide. Actual dates may vary significantly depending on your actual bleed, endometrial response, and clinic protocol. Always follow the dates and instructions given by your fertility clinic.